Will Derrick Henry enjoy the Giants’ run defense?

New York ranks 29th in run defense and gave up 176 yards and two touchdowns to the Eagles’ Saquon Barkley in October. Henry (1,407 yards) is chasing Barkley for the NFL rushing title, and December has historically been the most productive month of Henry’s career. Fresh off the bye week, Henry could be ready for a big day.

Will John Harbaugh continue his success after the bye week?

The Ravens are 13-3 under Harbaugh in games immediately following their bye week. This situation appears to be perfect for Baltimore – rested, healthy and against an opponent that has struggled. However, winning in the NFL can never be taken for granted, and the Ravens cannot afford any slip-ups in their quest to win the division.

Can the Ravens end their recent woes with backup quarterbacks?

Baltimore has already been defeated by backup quarterbacks Gardner Minshew (Raiders) and Jameis Winston (Browns). With Drew Lock (heel) wearing a walking boot this week, Giants head coach Brian Daboll has named replacement Tommy DeVito the starter for Sunday. DeVito won three straight starts last season and can be dangerous once he settles into a rhythm.