NFL Twitter reacts to Christian McCaffrey's loss against Bills due to injury

Dec 1, 2024; Orchard Park, New York, USA; San Francisco 49ers running back Christian McCaffrey (23) warms up before a game against the Buffalo Bills at Highmark Stadium. Mandatory attribution: Mark Konezny-Imagn Images

At the start of the game against the Buffalo Bills on Sunday Night Football, Christian McCaffrey got the San Francisco 49ers offense off to an early start.

Early in the second quarter against the Bills, McCaffrey rushed for 53 yards on seven carries. Earlier in the game, McCaffrey also caught two passes for 14 yards. However, after fending off an 18-yard carry, McCaffrey left the field on the next play, entering the field for a five-yard loss. McCaffrey quickly left the game, went to the medical tent and then to the locker room.

After halftime, Kyle Shanahan announced that McCaffrey would not return for the remainder of the game against the Bills.

Following McCaffrey’s injury, the NFL community on Twitter flooded social media with varying reactions. Here’s a look at what fans and analysts said on Twitter Sunday night.

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I wonder if the ’23 CMC ever comes back. This season is clearly over. Will his legs recover to normal after whatever this is? Or is it just over 🤷🏻‍♂️

— John Middlekauff (@JohnMiddlekauff) December 2, 2024

The previous one #CMC Knee injuries are likely to occur while playing. Concern about a PCL sprain of the right knee when the equipment is tight. On the next run he doesn’t feel right and falls to the ground. pic.twitter.com/aeQfmoS53x

— David J. Chao – ProFootballDoc (@ProFootballDoc) December 2, 2024

Seeing Christian McCaffrey go down gave me sports PTSD. As in the 2019 final, KD rolls and injures himself without physical contact. CMC finally looks like himself, same thing.

— Evan Giddings (@evanAgiddings) December 2, 2024

Christian McCaffrey –

Went down on his own, saving his right leg. Clearly something is wrong and it is safe to assume it is something affecting his right calf and/or Achilles.

I guess it was just a matter of time…
pic.twitter.com/lM1RMPz1r7

— Jeff Mueller, PT, DPT (@jmthrivept) December 2, 2024

It’s almost as if Kyle Shanahan should have gotten Christian McCaffrey back into action.

– Grant Cohn (@grantcohn) December 2, 2024

Injury to Christian McCaffrey –

The right knee hits the ground. There is a risk of PCL sprain or patella/bursa sprain due to the impact.

PCL would negatively impact his ROS (or they would shut him down). Bursa would allow him to play once the irritation/inflammation subsides. https://t.co/Pr3k14haNu pic.twitter.com/LNFaX95m2D

— Jeff Mueller, PT, DPT (@jmthrivept) December 2, 2024

Interesting. So this may actually have nothing to do with the Achilles/calf for CMC.

Insane momentum after a close tackle: What almost gave the 49ers a touchdown instead triggered a collapse and a Buffalo run that made it 21-3 https://t.co/NgzqIGlDTN

– David Lombardi (@LombardiHimself) December 2, 2024

This article originally appeared on Niners Wire: NFL Twitter reacts to Christian McCaffrey’s injury exclusion against Bills

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NFL Twitter reacts to Christian McCaffrey’s loss against Bills due to injury

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